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Life sciences. --- Biosciences --- Sciences, Life --- Science --- RNA --- Morfogènesi --- Estructura molecular
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Drosophila melanogaster (fruit fly) is a highly versatile model with a genetic legacy of more than a century. It provides powerful genetic, cellular, biochemical and molecular biology tools to address many questions extending from basic biology to human diseases. One of the most important questions in biology is how a multi-cellular organism develops from a single-celled embryo. The discovery of the genes responsible for pattern formation has helped refine this question and has led to other questions, such as the role of various genetic and cell biological pathways in regulating the process of pattern formation and growth during organogenesis. The Drosophila eye model has been extensively used to study molecular genetic mechanisms involved in patterning and growth. Since the genetic machinery involved in the Drosophila eye is similar to humans, it has been used to model human diseases and homology to eyes in other taxa. This updated second edition covers current progress in the study of molecular genetic mechanisms of pattern formation, mutations in axial patterning, genetic regulation of growth, and more using the Drosophila eye as a model.
Human genetics. --- Genetics --- Heredity, Human --- Human biology --- Physical anthropology --- Animal models in research. --- Animal genetics. --- Human Genetics. --- Animal Models. --- Animal Genetics and Genomics. --- Animal experimentation --- Biological models --- Laboratory animals --- Research --- Drosòfila --- Oftalmopaties --- Organogènesi --- Formació d'òrgans --- Organogènia --- Morfogènesi --- Neurobiologia del desenvolupament --- Malalties de l'ull --- Malalties dels ulls --- Malalties oculars --- Malalties --- Cataractes --- Conjuntivitis --- Infeccions oculars --- Manifestacions oculars de les malalties --- Oftàlmia --- Síndrome de Sjögren --- Trastorns de la visió --- Ull --- Drosophila --- Drosofílids --- Drosòfila melanogaster --- Drosòfila subobscura
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This atlas provides ultrastructural morphological images of human spermatozoa. Sperm morphology plays an essential role in sperm-oocyte interactions and early embryonic development, and human sperm ultrastructural morphology offers a valuable reference tool for assessing certain etiologies of male infertility and reproductive failure. However, the ultrastructural morphology of human sperm has not been systematically evaluated or thoroughly described in the literature. Using 470 original and unpublished images, the book shows various ultrastructural morphological phenotypes; defects of the sperm head, neck, middle piece, principal piece, and terminal piece; as well as artifacts of sperm ultrastructural morphology and phenomena related to inadequate preparation, demonstrating several sperm phenotypes and surface structural appearances for the first time. As such, it helps researchers and practitioners in andrology, reproductive medicine, and reproductive pathology gain a better understanding of human sperm ultrastructural morphology.
Human physiology. --- Andrology. --- Microscopy. --- Human Physiology. --- Biological Microscopy. --- Analysis, Microscopic --- Light microscopy --- Micrographic analysis --- Microscope and microscopy --- Microscopic analysis --- Optical microscopy --- Optics --- Generative organs, Male --- Human reproduction --- Men --- Human biology --- Medical sciences --- Physiology --- Human body --- Endocrine aspects --- Diseases --- Espermatozoides --- Semen --- Morfologia (Biologia) --- Estructura biològica --- Estructura en biología --- Forma biològica --- Morfologia comparada --- Anatomia comparada --- Homologia (Biologia) --- Malformacions --- Morfologia animal --- Morfologia vegetal --- Morfogènesi --- Humors corporals --- Espermatozous --- Gàmetes masculins --- Cèl·lules germinals --- Espermatogènesi --- Testicle
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This detailed new edition aims to provide a range of methods and protocols for studying vascular morphogenesis in vivo and in vitro to reflect up-to-date advances in the field. Of note, the book explores endothelial cell signaling is currently understood to promote fundamental cues for cell fate specification, embryo patterning, organ differentiation, and postnatal tissue remodeling. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and timely, Vascular Morphogenesis: Methods and Protocols, Second Edition will serve as an ideal guide to this area of study for a broad audience amongst cell biologists, anatomists, pathologists, and physiologists.
Morfogènesi --- Biologia del desenvolupament --- Desenvolupament (Biologia) --- Biologia --- Cicles vitals (Biologia) --- Desenvolupament de les plantes --- Desenvolupament infantil --- Envelliment --- Evolució --- Miogènesi --- Formació de models (Biologia) --- Genètica del desenvolupament --- Larves --- Neurobiologia del desenvolupament --- Creixement --- Embriologia --- Ontogènesi --- Morfogènia --- Diferenciació cel·lular --- Organogènesi --- Morfologia (Biologia) --- Developmental biology. --- Cytology. --- Developmental Biology and Stem Cells. --- Cell Biology. --- Cell biology --- Cellular biology --- Biology --- Cells --- Development (Biology) --- Growth --- Ontogeny --- Biologia del desenvolupament. --- Citologia --- Biologia cel·lular --- Citogenètica --- Citoquímica --- Migració cel·lular --- Cèl·lules --- Cèl·lules animals --- Ultraestructura (Biologia)
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This detailed book collects original protocols aimed at encouraging and stimulating the scientific community to design and produce models for the laboratory that mimic cell guidance conditions as they occur in vivo. The protocols collected describe powerful strategies to exploit chemical cues involved in cell differentiation processes. Special emphasis is given to the use of methods for purification and characterization of exosomes and other secreted vesicles, as well as micro and non-coding RNAs, that have been demonstrated to control the tuning of the in vivo micro and macro environment in order to ensure the optimal soluble environment in vitro. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Next Generation Culture Platforms for Reliable In Vitro Models: Methods and Protocols serves as an ideal guide for researchers working toward developing these vital testing models for preclinical studies.
Cultiu de teixits --- Cultiu de teixits in vitro --- Teixits (Histologia) --- Enginyeria de teixits --- Transformació cel·lular --- Cell differentiation. --- Regenerative medicine. --- Cell Differentiation. --- Regenerative Medicine and Tissue Engineering. --- Medicine --- Regeneration (Biology) --- Cell fate specification --- Cell specification --- Cells --- Differentiation of cells --- Fate specification of cells --- Specification of cells --- Morphogenesis --- Differentiation --- Fate specification --- Specification --- Diferenciació cel·lular --- Citodiferenciació --- Diferenciació de les cèl·lules --- Histogènesi --- Morfogènesi --- Genètica del desenvolupament
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Biology --- Biology, Experimental --- Biology. --- Biological Science Disciplines. --- Biology, Experimental. --- Experimental biology --- Biologic Sciences --- Biological Science --- Science, Biological --- Sciences, Biological --- Biological Sciences --- Life Sciences --- Biologic Science --- Biological Science Discipline --- Discipline, Biological Science --- Disciplines, Biological Science --- Life Science --- Science Discipline, Biological --- Science Disciplines, Biological --- Science, Biologic --- Science, Life --- Sciences, Biologic --- Sciences, Life --- biological sciences --- biology --- physiology --- cytology --- morphology --- genetics --- Life sciences --- Biomass --- Life (Biology) --- Natural history --- Experiments --- Biologia. --- Ciències biològiques --- Ciències de la vida --- Adaptació (Biologia) --- Anatomia --- Biodiversitat --- Bioelectrònica --- Bioenginyeria --- Bioespeleologia --- Biofísica --- Biogeografia --- Biolingüística --- Biologia aquàtica --- Biologia computacional --- Biologia de la conservació --- Biologia de poblacions --- Biologia del desenvolupament --- Biologia econòmica --- Biologia espacial --- Biologia experimental --- Biologia humana --- Biomatemàtica --- Biometria --- Bioquímica --- Biotecnologia --- Cèl·lules --- Citologia --- Criobiologia --- Cronobiologia --- Ecologia --- Embriologia --- Evolució (Biologia) --- Exobiologia --- Fecundació --- Filogènia --- Fisiologia --- Fotobiologia --- Generació espontània --- Genètica --- Geobiologia --- Immunologia --- Metabolisme --- Microbiologia --- Mimetisme (Biologia) --- Morfogènesi --- Mort (Biologia) --- Neurobiologia --- Ontogènesi --- Parasitologia --- Partenogènesi --- Protoplasma --- Psicobiologia --- Radiobiologia --- Regeneració (Biologia) --- Reproducció --- Sexualitat (Biologia) --- Simbiosi --- Variació (Biologia) --- Vitalisme --- Biomassa --- Ciències naturals --- Evolució --- Història de la biologia --- Il·lustració biològica --- Vida (Biologia)
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It is widely acknowledged that life has adapted to its environment, but the precise mechanism remains unknown since Natural Selection, Descent with Modification and Survival of the Fittest are metaphors that cannot be scientifically tested. In this unique text invertebrate and vertebrate biologists illuminate the effects of physiologic stress on epigenetic responses in the process of evolutionary adaptation from unicellular organisms to invertebrates and vertebrates, respectively. This book offers a novel perspective on the mechanisms underlying evolution. Capacities for morphologic alterations and epigenetic adaptations subject to environmental stresses are demonstrated in both unicellular and multicellular organisms. Furthermore, the underlying cellular-molecular mechanisms that mediate stress for adaptation will be elucidated wherever possible. These include examples of ‘reverse evolution’ by Professor Guex for Ammonites and for mammals by Professor Torday and Dr. Miller. This provides empirical evidence that the conventional way of thinking about evolution as unidirectional is incorrect, leaving open the possibility that it is determined by cell-cell interactions, not sexual selection and reproductive strategy. Rather, the process of evolution can be productively traced through the conservation of an identifiable set of First Principles of Physiology that began with the unicellular form and have been consistently maintained, as reflected by the return to the unicellular state over the course of the life cycle.
Evolutionary biology. --- Biodiversity. --- Paleontology . --- Microbiology. --- Invertebrates. --- Evolutionary Biology. --- Paleontology. --- Invertebrata --- Animals --- Microbial biology --- Biology --- Microorganisms --- Fossilogy --- Fossilology --- Palaeontology --- Paleontology, Zoological --- Paleozoology --- Historical geology --- Zoology --- Fossils --- Prehistoric animals in motion pictures --- Biological diversification --- Biological diversity --- Biotic diversity --- Diversification, Biological --- Diversity, Biological --- Biocomplexity --- Ecological heterogeneity --- Numbers of species --- Animal evolution --- Biological evolution --- Darwinism --- Evolutionary biology --- Evolutionary science --- Origin of species --- Evolution --- Biological fitness --- Homoplasy --- Natural selection --- Phylogeny --- Evolution (Biology) --- Morphogenesis. --- Morphogeny --- Organogenesis --- Embryology --- Morphology --- Morfogènesi --- Epigenètica --- Influència de l'home en la natura --- Efecte de l'home sobre la natura --- Efectes antropogènics sobre la natura --- Influència de l'home sobre el medi ambient --- Influència de l'home sobre la terra --- Ecologia humana --- Contaminació --- Desertització --- Petjada ecològica --- Genètica --- Morfogènia --- Biologia --- Diferenciació cel·lular --- Organogènesi --- Formació de models (Biologia) --- Morfologia (Biologia)
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Semiòtica --- Biologia --- Ciències biològiques --- Ciències de la vida --- Adaptació (Biologia) --- Anatomia --- Biodiversitat --- Bioelectrònica --- Bioenginyeria --- Bioespeleologia --- Biofísica --- Biogeografia --- Biolingüística --- Biologia aquàtica --- Biologia computacional --- Biologia de la conservació --- Biologia de poblacions --- Biologia del desenvolupament --- Biologia econòmica --- Biologia espacial --- Biologia experimental --- Biologia humana --- Biomatemàtica --- Biometria --- Bioquímica --- Biotecnologia --- Cèl·lules --- Citologia --- Criobiologia --- Cronobiologia --- Ecologia --- Embriologia --- Evolució (Biologia) --- Exobiologia --- Fecundació --- Filogènia --- Fisiologia --- Fotobiologia --- Generació espontània --- Genètica --- Geobiologia --- Immunologia --- Metabolisme --- Microbiologia --- Mimetisme (Biologia) --- Morfogènesi --- Mort (Biologia) --- Neurobiologia --- Ontogènesi --- Parasitologia --- Partenogènesi --- Protoplasma --- Psicobiologia --- Radiobiologia --- Regeneració (Biologia) --- Reproducció --- Sexualitat (Biologia) --- Simbiosi --- Variació (Biologia) --- Vitalisme --- Biomassa --- Ciències naturals --- Evolució --- Història de la biologia --- Il·lustració biològica --- Vida (Biologia) --- Semiologia (Lingüística) --- Semàntica --- Simbolisme --- Anàlisi del discurs --- Intertextualitat --- Multimodalitat --- Onomasiologia --- Simbolisme fònic --- Semiòtica de l'arquitectura --- Archaeology. --- Archeology --- Anthropology --- Auxiliary sciences of history --- History --- Antiquities
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Biologia --- Tecnologia de la informació --- Information technology --- Biology --- Philosophy. --- Noves tecnologies de la informació i de la comunicació --- Tecnologies de la informació i la comunicació --- Tecnologia de la comunicació i de la informació --- TIC --- AcTIC --- Alfabetització tecnològica --- Autopistes de la informació --- Bretxa digital --- Economia de la informació --- Gestió del coneixement --- Ciències biològiques --- Ciències de la vida --- Adaptació (Biologia) --- Anatomia --- Biodiversitat --- Bioelectrònica --- Bioenginyeria --- Bioespeleologia --- Biofísica --- Biogeografia --- Biolingüística --- Biologia aquàtica --- Biologia computacional --- Biologia de la conservació --- Biologia de poblacions --- Biologia del desenvolupament --- Biologia econòmica --- Biologia espacial --- Biologia experimental --- Biologia humana --- Biomatemàtica --- Biometria --- Bioquímica --- Biotecnologia --- Citologia --- Criobiologia --- Cronobiologia --- Ecologia --- Embriologia --- Evolució (Biologia) --- Exobiologia --- Fecundació --- Filogènia --- Fisiologia --- Fotobiologia --- Generació espontània --- Genètica --- Geobiologia --- Immunologia --- Metabolisme --- Microbiologia --- Mimetisme (Biologia) --- Morfogènesi --- Mort (Biologia) --- Neurobiologia --- Ontogènesi --- Parasitologia --- Partenogènesi --- Protoplasma --- Psicobiologia --- Radiobiologia --- Regeneració (Biologia) --- Reproducció --- Sexualitat (Biologia) --- Simbiosi --- Variació (Biologia) --- Vitalisme --- Biomassa --- Ciències naturals --- Evolució --- Història de la biologia --- Il·lustració biològica --- Vida (Biologia) --- IT (Information technology) --- Technology --- Telematics --- Information superhighway --- Knowledge management --- Vitalism
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Fungi. --- Mycology. --- Fungal biology --- Fungology --- Fungus biology --- Botany --- Microbiology --- Fungi --- Fungal kingdom --- Fungus kingdom --- Funguses --- Mycobiota --- Mycota --- Cryptogams --- Mycology --- Micologia --- Biotecnologia --- Biologia --- Ciències biològiques --- Ciències de la vida --- Adaptació (Biologia) --- Anatomia --- Biodiversitat --- Bioelectrònica --- Bioenginyeria --- Bioespeleologia --- Biofísica --- Biogeografia --- Biolingüística --- Biologia aquàtica --- Biologia computacional --- Biologia de la conservació --- Biologia de poblacions --- Biologia del desenvolupament --- Biologia econòmica --- Biologia espacial --- Biologia experimental --- Biologia humana --- Biomatemàtica --- Biometria --- Bioquímica --- Citologia --- Criobiologia --- Cronobiologia --- Ecologia --- Embriologia --- Evolució (Biologia) --- Exobiologia --- Fecundació --- Filogènia --- Fisiologia --- Fotobiologia --- Generació espontània --- Genètica --- Geobiologia --- Immunologia --- Metabolisme --- Microbiologia --- Mimetisme (Biologia) --- Morfogènesi --- Mort (Biologia) --- Neurobiologia --- Ontogènesi --- Parasitologia --- Partenogènesi --- Protoplasma --- Psicobiologia --- Radiobiologia --- Regeneració (Biologia) --- Reproducció --- Sexualitat (Biologia) --- Simbiosi --- Variació (Biologia) --- Vitalisme --- Biomassa --- Ciències naturals --- Evolució --- Història de la biologia --- Il·lustració biològica --- Vida (Biologia) --- Enginyeria --- Antropometria --- Biosíntesi --- Biotecnologia agrícola --- Biotecnologia alimentària --- Biotecnologia farmacèutica --- Biotecnologia marina --- Biotecnologia microbiana --- Enginyeria bioquímica --- Enginyeria sanitària --- Ergonomia --- Indústries biotecnològiques --- Microbiologia industrial --- Reproducció assistida --- Bioreactors --- Botànica --- Micologia mèdica
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